3D-Printed Models of Human Pulmonary Vascular Disease

Date: 7/1/20

Pulmonary arterial hypertension (PAH) is a type of high blood pressure that affects your heart and lungs. It is a progressive and incurable vascular disease characterized by remodeling of and narrowing of the blood vessels. Female patients are four times more likely to be diagnosed with PAH than male patients.

Our lab has developed a new class of phototunable biomaterials and 3D bioprinting techniques that allow us to mimic PAH blood vessels in vitro. This advanced platform provides the foundation for models of increasing complexity that reveal novel mechanistic insights into sex-specific disease prevention and intervention.











Lab members working on this project:

Duncan Davis-Hall, MS (Bioengineering PhD Student)
Mikala Mueller, BS (Bioengineering MS Student)

Collaborators:
Adam Feinberg, PhD, Carnegie Mellon University
Kurt Stenmark, MD, University of Colorado, Anschutz Medical Campus
Lori Walker, PhD, University of Colorado, Anschutz Medical Campus
Steven Lammers, PhD, University of Colorado, Anschutz Medical Campus
Keith Neeves, PhD, University of Colorado, Anschutz Medical Campus
Vitaly Kheyfets, PhD, University of Colorado, Anschutz Medical Campus

Funding sources: